She had gray hair with a leathery face.
She was one of the Wise Ones that opposed Sevanna's acting as clan chief of the Shaido.
She was among the Wise Ones who had made an alliance with the White Tower. After Rand al'Thor was captured by the White Tower in accordance with the alliance, Desaine was murdered by her fellow Shaido Wise Ones under Sevanna's command both to quell the opposition of the Shaido Wise Ones against Sevanna's way and to use her death as a feign and a pretext.
Later, before Dumai's Wells battle, Sevanna used her death to convince both the Wise Ones and the Shaido to fight the Aes Sedai (fighting Aes Sedai was considered out of custom) treacherously claiming that Desaine was brutally murdered by the Aes Sedai themselves and they needed to avenge her for the Shaido's honor.